About us
Translation quality controls eliminate aberrant proteins to maintain protein homeostasis and normal cell function. Improving the accuracy of translation and preventing the production of abnormal proteins is a practical approach for suppressing a series of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. We analyze the molecular mechanism of quality control mechanisms that suppress abnormal proteins and clarify drug discovery’s molecular basis. We propose that the increase in translation accuracy and the enhancement of translation quality control mechanisms are possible strategies to prevent abnormal protein production and prolong healthy life expectancy.
